ClusterMine360: A Database of Microbial PKS/NRPS Biosynthesis

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Cluster Details

Accession # U24241
Cluster Bases
If cluster is a subsegment of the GenBank sequence.
Name of Compound Family Soraphen
Related Compound Families
Pathway Type PKS - Type I
PKS - Type I (Modular)
Producing Organism Sorangium cellulosum
Phylum Proteobacteria (Delta)
Organism Lineage
Description Sorangium cellulosum acyl-CoA dehydrogenase (sorE), beta-hydroxybutyryl-CoA dehydrogenase (sorD), putative methoxymalonyl-CoA synthase (sorC), reductase (sorR), soraphen polyketide synthase A (sorA), soraphen polyketide synthase B (sorB), O-methyltransferase (sorM), beta-mannanase, and xylanse-arabinofuranosidase bifunctional enzyme genes, complete cds; and unknown genes.
Sequencing References
Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26. Gene 2002 Feb; 285(1-2): 257-67. PMID: 12039053
A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes. J. Bacteriol. 1995 Jul; 177(13): 3673-9. PMID: 7601830
Other References
Domains Toggle View Domains
antiSMASH Status View
Status of Domain Sequence Extraction Completed
Contributor Kyle Conway
Boddy Lab

Last modified Saturday, 08 September 2012 21:57 by System Admin