Accession # |
HM038106.1
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Cluster Bases If cluster is a subsegment of the GenBank sequence. |
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Name of Compound Family |
Actinomycin
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Synonyms |
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Related Compound Families |
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Pathway Type |
NRPS
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Characteristics |
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Producing Organism |
Streptomyces anulatus
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Phylum |
Actinobacteria
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Organism Lineage |
Actinobacteria Actinobacteridae Actinomycetales Streptomycineae Streptomycetaceae Streptomyces
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Description |
Streptomyces anulatus actinomycin biosynthetic gene cluster, partial sequence. |
Sequencing References |
The actinomycin biosynthetic gene cluster of Streptomyces chrysomallus: a genetic hall of mirrors for synthesis of a molecule with mirror symmetry. J. Bacteriol. 2010 May; 192(10): 2583-95. PMID: 20304989
Molecular characterization of the genes of actinomycin synthetase I and of a 4-methyl-3-hydroxyanthranilic acid carrier protein involved in the assembly of the acylpeptide chain of actinomycin in Streptomyces. J. Biol. Chem. 1999 Apr; 274(18): 12508-16. PMID: 10212227
Construction and in vitro analysis of a new bi-modular polypeptide synthetase for synthesis of N-methylated acyl peptides. Chem. Biol. 2000 Apr; 7(4): 287-97. PMID: 10780924
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Other References |
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Domains
|
View Domains
Download (.fasta)
|
Domain Type
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Identifier
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Length (AA)
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Additional Info
|
Download
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Adenylation
|
acmA
|
364
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A or AT Prediction: nrp
|
Download
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Condensation: Starter
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acmB
|
297
|
|
Download
|
Adenylation
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acmB
|
413
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A or AT Prediction: thr
|
Download
|
PCP
|
acmB
|
69
|
|
Download
|
Condensation: LCL
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acmB
|
302
|
|
Download
|
Adenylation
|
acmB
|
393
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A or AT Prediction: val
|
Download
|
PCP
|
acmB
|
68
|
|
Download
|
Epimerization
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acmB
|
314
|
|
Download
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NRPS-COM: Cterm
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acmB
|
20
|
|
Download
|
Cglyc
|
acmC
|
297
|
|
Download
|
Adenylation
|
acmC
|
408
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A or AT Prediction: pro
|
Download
|
PCP
|
acmC
|
69
|
|
Download
|
Condensation: LCL
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acmC
|
300
|
|
Download
|
Adenylation
|
acmC
|
403
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A or AT Prediction: gly
|
Download
|
nMT
|
acmC
|
223
|
|
Download
|
PCP
|
acmC
|
69
|
|
Download
|
Condensation: LCL
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acmC
|
302
|
|
Download
|
Adenylation
|
acmC
|
394
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A or AT Prediction: val
|
Download
|
nMT
|
acmC
|
223
|
|
Download
|
PCP
|
acmC
|
69
|
|
Download
|
Thioesterase
|
acmC
|
244
|
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Download all of the sequences above (.zip)
|
antiSMASH Status |
View
|
Status of Domain Sequence Extraction |
Completed
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Contributor |
Kyle Conway Boddy Lab
|